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PCIRN PRINCIPAL INVESTIGATORS Dr. Scott Halperin, Nominated Principal Investigator, PCIRN Dr. Halperin is a Professor of Pediatrics and Microbiology and Immunology at Dalhousie University and the Head of Pediatric Infectious Diseases at the IWK Health Centre in Halifax. He has lived in Halifax since 1985 where he is the director of the Canadian Center for Vaccinology. Dr. Halperin is also Co-Principal Investigator of the IMPACT network. His research focuses on the diagnosis, treatment, and prevention of pertussis and other vaccine-preventable diseases. Dr. David Scheifele, Co-Principal Investigator, Clinical Trials Network Dr. Scheifele is one of the original founders of the Vaccine Evaluation Center at the Child and Family Research Institute, and has been the Director for the past 25 years. Dr. Scheifele is a founding investigator of IMPACT, a surveillance network of 12 pediatric hospitals across Canada that actively monitors certain vaccine-preventable diseases and adverse events following immunization. He is the founding chair of the Canadian Association for Immunization Research and Evaluation. In 2013 he was appointed to the Order of Canada for his contributions to child health through immunization. Dr. Mark Loeb, Co-Principal Investigator, Clinical Trials Network Dr. Loeb is a Professor in the Departments of Pathology and Molecular Medicine and Clinical Epidemiology and Biostatistics at McMaster University. He is Division Director for Infectious Diseases and holds the Michael G DeGroote Chair in Infectious Diseases. Current projects include an NIH population genetics research program on dengue and a CIHR funded cluster randomized controlled trial to reduce the spread of infuenza by immunizing children in Hutterite colonies. Dr. Joanne Langley, Co-Principal Investigator, Clinical Trials Network Dr. Joanne Langley is a Professor of Pediatrics (Division of Infectious Diseases) and Community Health and Epidemiology at Dalhousie University, and the CIHR-GSK Chair in Pediatric Vaccinology. Dr. Langley currently serves as Associate Director (Clinical Evaluation Unit) of the Canadian Center for Vaccinology, and as Medical Director of the Infection Prevention and Control Program at the IWK Health Centre. Dr. Langley’s main research interests are in the epidemiology and prevention of respiratory infections, particularly Respiratory Syncytial Virus and infuenza. Dr. Julie Bettinger, Principal Investigator, National Ambulatory Network Dr. Bettinger is an Associate Professor at the Vaccine Evaluation Center in the Department of Pediatrics at the University of British Columbia and a Michael Smith Foundation for Health Research Scholar. Her research interests include vaccine safety and vaccine preventable diseases (specifcally meningococcal and pneumococcal invasive infections), as well as attitudes and beliefs around immunization uptake and use. She is the epidemiologist for the Canadian Immunization Monitoring Program, Active (IMPACT), an active surveillance network for vaccine preventable diseases and vaccine adverse events in 12 tertiary care pediatric hospitals across Canada. Dr. Jeff Kwong, Principal Investigator, Program Delivery and Evaluation Network Dr. Kwong is a Scientist at the Institute for Clinical Evaluative Sciences (ICES) and at Public Health Ontario, a family physician with the Toronto Western Family Health Team, and an Associate Professor in the Department of Family and Community Medicine and the Dalla Lana School of Public Health at the University of Toronto. Key research interests include infectious diseases epidemiology and health services research using linkable data, infuenza vaccine and vaccination program evaluation, and assessing the burden of infectious diseases. Dr. Gaston De Serres, Principal Investigator, Special Immunization Clinics Network Dr. De Serres is a Medical Epidemiologist at the Institute National de Santé Publique du Québec and a professor of Epidemiology at the Faculty of Medicine at Laval University. Dr. De Serres works in the area of control and prevention of infectious disease with a focus on vaccine-preventable diseases and respiratory infections, vaccine effectiveness and vaccine safety. Dr. Shelly McNeil, Co-Principal Investigator, Serious Outcomes Surveillance (SOS) Network Dr. McNeil is a Professor of Medicine and an Infectious Diseases Consultant at the QEII Health Sciences Centre in Halifax. Dr. McNeil is cross-appointed as an Assistant Professor of Pediatrics. She is a Clinical Investigator at the Canadian Center for Vaccinology, Halifax, where her research focuses on health policy, the evaluation of vaccine-preventable diseases in the elderly and in pregnant women and in clinical trials of new vaccines targeted at adolescent and adult populations. Dr. Melissa Andrew, Co-Principal Investigator, Serious Outcomes Surveillance (SOS) Network Dr. Andrew is a staff geriatrician and Assistant Professor of Geriatric Medicine at Dalhousie University, and a member of the CCfV. Drawing on her clinical experience in Geriatric Medicine as well as her training in Public Health, Dr. Andrew’s work with CCfV aims to apply concepts which are important to the health of seniors, such as frailty and social vulnerability, to key health questions such as vaccine effectiveness and outcomes of acute infections. Dr. Brian Ward, Principal Investigator, Reference Laboratory Network Dr. Ward is currently a professor of medicine and microbiology at McGill University. He is the Co-Director of the McGill Vaccine Study Centre, Deputy Director of the Research Institute of the McGill University Health Centre (Fundamental Science), Associate Director of the JD MacLean Center for Tropical Diseases and Medical Director of the (Health Canada) National Reference Center for Parasitology. His research in vaccine development, parasite diagnostics and global health are supported by Canadian and international funding agencies as well as private foundations and industry. PHAC/CIHR INFLUENZA RESEARCH NETWORK