Hospital admissions for acute respiratory tract infections among infants from Nunavut and the burden of respiratory syncytial virus: a 10-year retrospective cohort study Hospital admissions for acute respiratory tract infections among infants from Nunavut and the burden of respiratory syncytial virus: a 10-year retrospective cohort study
Background: Nunavut is a northern Canadian territory where a high proportion of infants are admitted to hospital with acute respiratory tract infection (ARI). Previous studies have been limited in regional and/or short duration of coverage. This study aimed to estimate the incidence rate, microbiology and outcomes of ARI hospitalizations in Nunavut infants. Methods: We conducted a retrospective cohort study of infants aged 6 months. Compared with non-RSV admissions, infants with RSV had higher odds of admission into intensive care, oxygen therapy, CPAP/BiPAP respiratory support and length of hospital stay over a week. Interpretation: Understanding the high burden of ARI among Nunavut infants can inform health policy and serve as a baseline for assessing the impact of any new interventions targeting infant ARIs. Funding: Public Health Agency of Canada and Canadian Institutes of Health Research via the Canadian Immunization Research Network (CNF 151944).
Background: Nunavut is a northern Canadian territory where a high proportion of infants are admitted to hospital with acute respiratory tract infection (ARI). Previous studies have been limited in regional and/or short duration of coverage. This study aimed to estimate the incidence rate, microbiology and outcomes of ARI hospitalizations in Nunavut infants. Methods: We conducted a retrospective cohort study of infants aged 6 months. Compared with non-RSV admissions, infants with RSV had higher odds of admission into intensive care, oxygen therapy, CPAP/BiPAP respiratory support and length of hospital stay over a week. Interpretation: Understanding the high burden of ARI among Nunavut infants can inform health policy and serve as a baseline for assessing the impact of any new interventions targeting infant ARIs. Funding: Public Health Agency of Canada and Canadian Institutes of Health Research via the Canadian Immunization Research Network (CNF 151944).