Impact of repeated vaccination against influenza on influenza antibody titres and laboratory-confirmed illness
- – To determine the vaccination history (starting in 1990, as possible) of participants of the Influenza Cohort Study, which was conducted in 2010/11-2013/14. This data will be used to compare the pre-season HI titres of participants by influenza type/subtype (A/H1N1, A/H3N2, and B) by influenza vaccination in the current season and vaccination history, adjusting for age, sex, season, and study site.
- – To compare the VE against lab-confirmed influenza by vaccination in the current season and vaccination history, adjusting for the participant’s age, sex, season, and study site.
- – Responses of up to 5% of consenting participants will be compared with Occupational Health records in sites with available records to assess recall bias.
Dr. Brenda Coleman