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CIRN NETWORKS






Serious Outcomes


Surveillance Network (SOS)





The SOS Network was established in 2009 to prospectively monitor
annual seasonal infl uenza vaccine eff ectiveness (VE) in the prevention
of hospitalization of adults with confi rmed infl uenza illness. SOS is also

examining the burden of infl uenza illness to the health care system among
adults hospitalized by this disease. Since 2009, SOS has established a
network of Canadian sites with the capacity to actively conduct active
surveillance of hospitalizations attributable to several vaccine preventable
illnesses. The network is comprised of 14 sites located in BC, Ontario,

Quebec, New Brunswick, and Nova Scotia.




The primary purpose of the network is to gather data
regarding the incidence and severity of illness in adults
hospitalized due to infl uenza and to assess the VE of
annual vaccination. SOS also assesses the impact of
frailty prior to illness on the outcomes for adults over
65 years of age. Additionally, SOS enrolls adults with
Community Acquired Pneumonia (CAP) or Invasive
Pneumococcal Disease (IPD) to assess the incidence
and impact of these illnesses, particularly those caused
by Streptococcus pneumonaie.

Investigators for the SOS Network span a range of
specialties: Infectious Disease Specialists, Geriatricians,
Microbiologists, Statisticians, Epidemiologists and Internal
Medicine Specialists. This Network is designed to provide
surveillance to ensure that as a new vaccine becomes
available, a method is in place to identify whether there
are changes in the incidence and severity of the disease
and whether there are changes in the strains responsible of Canada, and also weekly province-specifi c reporting
for severe diseases. to Institut national de santé publique du Québec in
Quebec. Interim estimates of vaccine effectiveness
Demonstrating its continuing value as a real-time from the network were published in Eurosurveillance in
reporter of vaccine effectiveness, during the current February 2015, and found that the seasonal vaccine was
infl uenza season SOS provided weekly, reports on largely ineffective in preventing disease from the strains
national infl uenza activity to the Public Health Agency circulating in 2014-15.




2015 ANNUAL REPORT 5
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