COVID-19 Vaccine
2nd Dose Mix-and-Match

The initial MOSAIC study was commenced to compare the effectiveness, safety and acceptability of different dosing schedules of the first two doses of COVID-19 vaccines. That study began in June 2021 and is ongoing at 7 clinical sites in Canada where 195 participants were enrolled and received either both of their vaccines or the second authorized COVID-19 vaccine. Assessment of the safety, tolerability and immune response in these participants is ongoing.


You can take part in this study if:

  1. You are 18 years of age and older
  2. You are available for all the study visits.
  3. You are in good health with stable health conditions.
  4. You are not pregnant.
  5. You have a record of your previous doses of the authorized COVID-19 vaccines you received.

Co-Principle Investigator

Dr. Manish Sadarangani

Dr. Manish Sadarangani is Director of the Vaccine Evaluation Center at the BC Children’s Hospital Research Institute and an Associate Professor in the Division of Infectious Diseases, UBC Department of Pediatrics.